Stanley Botchway

UKRI-STFC Fellow and Research Lead

Stan joined the CLF in 1998 as the Laser Microscopy and Imaging Facility Manager and Biosciences Lead following a Postdoctoral fellowship at Harvard Medical School. He has developed novel laser applications including an ultrafast laser microbeam for cellular DNA damage and repair studies, advanced imaging instrumentation and spectroscopy including Multiphoton Fluorescence and Phosphorescence – Lifetime Imaging Microscopy (FLIM-PLIM). His research has centred on the application of new probes for cellular imaging and studies on cancer protein interactions. He is currently a principal investigator. Stan also supports a quantum biology research team funded by The Guy Foundation. He has several patents and licences granted to CRUK- Ximbio. He has over 190 peer-reviewed publications.

His current research interests include:

the development of advanced microscopy including multiphoton microscopy, fluorescence anisotropy imaging, phosphorescence (PLIM) and Fluorescence lifetime imaging microscopy (FLIM) for the characterisation of the environment of biomolecules in cells and protein-protein interactions.
DNA damage induction by multiphoton process to mimic the effects of ionising radiation and subsequent repair studies by fluorescent protein detection in live cells.
characteristics of mTOR signalling pathway using advanced imaging, spectroscopy and time resolved microscopy.
the development of quantum technologies for biological sciences.

Awards and Honours

Fellow of Royal Society of Chemistry, UK (Elected)
Royal Microscopical Society (RMS) Board member
ICRR President Young Investigator Award
ARR President Young Investigator Award
Elected Full member, Radiation Research Society, USA
Full member, Association of Radiation Research, UK
Visiting Professor, Oxford Brookes University, Faculty of Health and Life Sciences
Honorary Senior Research Fellow in the School of Biological Sciences, University of Bristol

Scientific Advisor to The Guy Foundation
Editorial Board Member for MDPI-Instruments
Editorial Board Member for Frontiers Publishing
EPSRC Associate College Membership