Sarah’s current research interests range from using the FLImP technique to look at the structure of receptors, e.g. the Epidermal Growth Factor Receptor, on the cell membrane to lightsheet imaging of organoids, spheroids and whole tissues. She recently developed an interest in extracellular vesicles and how to image the proteins and biomarkers on and within the EVs. Sarah is also interested in developing and expanding capabilities of single-molecule techniques and FLImP adjacent techniques to research different scientific questions.
Sarah Needham
Link Scientist? STFC Senior Scientist?
Sarah joined STFC as a postdoctoral researcher in 2005 and the CLF in 2008. She currently provides scientific support to academic and industrial groups from sample preparation through to imaging and analysis. Sarah obtained a BSC Hons and MSC in Biomedical Science from University of Wolverhampton, before completing a PhD in Biology at University of York (CASE studentship with GlaxoSmithKline). Sarah’s main expertise is in single-molecule techniques. She co-developed the FLImP technique, but also has experience in lightsheet imaging, STORM to image extracellular vesicles, and other super-resolution techniques.