Laura C Zanetti Domingues

Senior Staff Scientist

Laura (preferred pronouns xe/xem) joined the CLF in 2010 as a joint PhD student in Cancer Studies with King’s College London. Since then, xe has developed single-particle tracking assays to study proteins inside live cells, before moving on to spearhead the development of cryo-vEM and cryo-CLEM techniques.

Laura’s current research interests are directed towards the study of structure-function relationships underlying pathological processes in intact biological systems using (cryo-)vEM and (cryo-)CLEM techniques. In particular, xe is interested in the role of endocytosis, membrane contact sites and liquid phase separation in organising cellular signalling in cancer and beyond.

Zanetti-Domingues LC, et al., Methods Cell Biol. 2024;187:249-292.

Iyer RS, et al., Nat Commun. 2024 Mar 19;15(1):2130

Qiu C, et al., ACS Catal. 2023 Nov 28;13(24):15956-15966.