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Laura C Zanetti Domingues

Senior Staff Scientist

Laura (preferred pronouns xe/xem) joined the CLF in 2010 as a joint PhD student in Cancer Studies with King’s College London. Since then, xe has developed single-particle tracking assays to study proteins inside live cells, before moving on to spearhead the development of cryo-vEM and cryo-CLEM techniques.

Laura’s current research interests are directed towards the study of structure-function relationships underlying pathological processes in intact biological systems using (cryo-)vEM and (cryo-)CLEM techniques. In particular, xe is interested in the role of endocytosis, membrane contact sites and liquid phase separation in organising cellular signalling in cancer and beyond.

Selected publications

Toward quantitative super-resolution methods for cryo-CLEM

LC Zanetti-Domingues et al


Drug-resistant EGFR mutations promote lung cancer by stabilizing interfaces in ligand-free kinase-active EGFR oligomers

RS Iyer et al


Compositional Evolution of Individual CoNPs on Co/TiO2 during CO and Syngas Treatment Resolved through Soft XAS/X-PEEM

C Qiu et al

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